通过皮肤运输二氧化碳的动态建模,使用一个Capnometry腕带
Pierre Grangeat1, Maria-Paula Duval Comsa1, Anne Koenig1
1CEA, Leti, MINATEC Campus, Université Grenoble Alpes, F-38000 Grenoble, France.
Sensors (Basel, Switzerland)
|July 14, 2023
概括
这项研究引入了一种使用非分散性红外 (NDIR) 传感器进行家庭患者监测的新型测腕带. 卡尔曼波器可以实时估计血液中的二氧化碳 (CO2) 水平,展示了该技术.
科学领域:
- 生物医学工程 生物医学工程
- 生理监测 生理监测
- 光学传感技术的技术.
背景情况:
- 患者的家庭监测需要进行非侵入性和持续的生理测量.
- 测量二氧化碳 (CO2) 水平的度测量对于评估呼吸功能至关重要.
- 现有的空气测量仪器可能不适合在家方便长期使用.
研究的目的:
- 开发和验证一种新型的测腕带,用于实时监测血液二氧化碳度.
- 模拟血液与新型传感器架构之间二氧化碳交换的时间动态.
- 评估使用卡尔曼波器在可穿戴设备中准确估计二氧化碳的可行性.
主要方法:
- 提出了一种新的腕带架构,集成非分散性红外 (NDIR) 传感与开放室和空气流.
- 开发了一种使用对流-扩散方程进行二氧化碳转运的多间隔模型 (血液,皮肤,测量细胞,收集细胞).
- 实现了一个状态空间表示,使用马科夫模型和一个包含一级自回归模型的增强系统.
- 使用卡尔曼波器对血液二氧化碳度进行递归估计.
主要成果:
- 建立了一个数学模型来描述手腕带收集单元内的二氧化碳动态.
- 卡尔曼波器成功估计了随着时间的推移递归的血液二氧化碳度.
- 基于临床数据的模拟证明了拟议的度计腕带概念的可行性.
- 该系统显示了对动脉二氧化碳血压实时监测的潜力.
结论:
- 开发的测腕带架构和卡尔曼过方法显示出对非侵入性,实时的二氧化碳监测的前景.
- 这项技术可以实现有效的远程患者管理,并改善医疗保健的可访问性.
- 需要进一步的临床验证,以确认该设备在不同患者群体中的性能和可靠性.
关键词:
卡尔曼过器可以过.增强动态系统增强动态系统血液中的二氧化碳度.标本测量法 (capnometry) 是一种测量法.二氧化碳通过皮肤施加压力.分隔式模型的模型.持续的监控,持续的监控.卷积扩散方程的对流扩散方程.状态空间马科维模型穿戴式医疗设备是一种可穿戴的医疗设备.更多相关视频
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