生存推算 纳入一般人口死亡率 使用过度危险和治愈模型:一个教程
Michael J Sweeting1, Mark J Rutherford2, Dan Jackson1
1Statistical Innovation, AstraZeneca, Cambridge, UK.
概括
结合一般人口死亡数据的过度危险 (EH) 方法可以减少成本效益分析的长期生存推断中的不确定性. 当治愈是可信的时,EH治愈模型特别有效,显著降低了生存估计的变化.
科学领域:
- 卫生经济建模健康经济建模
- 生物统计学 生物统计学
- 对生存分析的分析.
背景情况:
- 在成本效益分析中的参数生存模型可以产生不一致的推断和决策不确定性.
- 过度危险 (EH) 方法通过整合一般人口死亡率数据来减少模型不确定性提供了一个潜在的解决方案.
- 本综述侧重于在长期生存估计中使用EH方法的实际考虑.
结论:
- 对于生存推断来说,EH方法非常有价值,特别是在癌症中,随着时间的推移,多余的危险可能会减少.
- 当治愈是可信的时,EH治愈模型是有益的,从而减少了外推变性.
- 电子健康方法证明了对寿命错误规范的稳定性.
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