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在接受脊髓瘤手术的患者中,术后手术部位感染的危险因素

Baoquan Xin^1,2, Shuang Cao³, Guangjian Bai^1,2

¹School of Health Science and Engineering, University of Shanghai for Science and Technology.

Clinical spine surgery

|July 14, 2023

概括

修订状态,广泛的脊髓融合 (≥4级) 和骨质水泥使用在脊髓瘤再手术中增加了手术部位感染 (SSI) 的风险. 识别这些因素有助于预防术后并发症.

科学领域:

脊柱外科手术脊柱外科手术
在瘤学瘤学.
传染病传染病传染病传染病

背景情况:

手术部位感染 (SSI) 是脊髓手术后的一个严重并发症.
在接受重新手术的脊髓瘤患者中,SSI增加了死亡率,住院时间和成本.

研究的目的:

在需要重新手术的脊髓瘤患者中,确定术后手术部位感染 (SSI) 的危险因素.
分析临床数据以确定该患者队列中SSI的独立预测因子.

主要方法:

对202名脊柱瘤患者进行了回顾性比较病例控制研究,这些患者在2008-2018年间接受了手术.
101名SSI和重新手术的患者 (SSI组) 与101名没有SSI的患者 (对照组) 相匹配.
使用后勤回归分析来确定与SSI相关的风险因素.

主要成果:

多变量分析显示修订状态 (B=1.430,P=0.028) 是一个重要的风险因素.
4个或更多脊柱水平的融合 (B=0.963,P=0.006) 与增加SSI风险有关.
使用骨水泥 (B=0.739,P=0.046) 也被确定为SSI的一个独立风险因素.

结论:

修订状态,广泛的脊髓融合 (≥4级) 和骨是重新手术脊髓瘤患者SSI的独立风险因素.
这些发现可以为在高风险的外科病例中减轻SSI风险的策略提供信息.
进一步的研究可能会探索在接受修复脊柱瘤手术的患者中减少SSI的具体干预措施.

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