患有唐氏综合征的青少年患者的脊椎病:曲线大小与功能水平之间的相关性
Rosa M Egea-Gámez1, María Galán-Olleros2, Ignacio Martínez-Caballero2
1Spinal Unit, Orthopaedic Surgery and Traumatology Department.
Clinical spine surgery
|July 14, 2023
概括
患有唐氏综合征 (DS) 和功能水平较差的患者有增加的脊柱形曲线严重程度和手术风险. 这凸显了功能评估在管理脊柱形患者中的重要性.
科学领域:
- 整形外科 整形外科 整形外科
- 遗传学 遗传学 是一个
- 发育儿科 发育儿科
背景情况:
- 与一般人群相比,患有唐氏综合征 (DS) 的患者表现出更高的脊椎病发病率.
- 功能水平对DS中脊柱形的特征和严重性的影响仍然不清楚.
研究的目的:
- 研究唐氏综合征 (DS) 患者的功能水平和脊柱形之间的关系.
- 确定功能状态是否会影响脊柱状的严重程度以及DS患者手术干预的必要性.
主要方法:
- 来自儿科推中心数据库的46名唐氏综合征和脊椎病患者的回顾性观察研究.
- 根据步态和粗体运动技能,患者被分为两种功能水平.
- 使用全脊椎站立放射图来测量冠状和斜脊柱的脊柱参数;多变量分析评估了与功能水平的关联.
主要成果:
- 在较差的功能水平 (II级) 和增加的曲线大小 (36.9°与18.9°,P=0.001) 之间发现了统计学上显著的关联.
- 具有II级功能状态的患者显示需要手术的可能性明显更高 (P=0.016).
- 没有观察到功能水平和脊柱平衡,曲线位置或胸切除术史之间的显著关系.
结论:
- 患有唐氏综合征和较低功能水平的青少年有更严重的脊柱形曲线的倾向.
- 在DS患者中,功能状况较差与需要为脊柱病进行手术纠正的风险增加有关.
- 功能水平评估可以为唐氏综合征患者的脊柱形提供量身定制的后续策略.
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