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Updated: Jul 23, 2025

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在人类肝脏显微体中,苏博洛辛对CYP1A2的选择性抑制作用

Sanjita Paudel1, Hyoje Jo1, Taeho Lee1

  • 1BK21 FOUR Community-Based Intelligent Novel Drug Discovery Education Unit, College of Pharmacy, Kyungpook National University, Daegu, Republic of Korea.

Biopharmaceutics & drug disposition
|July 14, 2023
PubMed
概括

苏贝罗辛是Citropsis articulata中的一种化合物,可以选择性地抑制细胞染色体P450 1A2 (CYP1A2). 这表明,当与由CYP1A2.2.代谢的药物一起服用时,可能存在草药相互作用.

关键词:
在CYP1A2中.竞争性抑制是一种竞争性的抑制.人类肝脏微粒细胞可逆抑制剂的可逆抑制剂这种药物是suberosin.

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