勃起功能障碍和血清B12水平之间的相关性:一个136个病例的横截面分析
Mevlüt Keleş1, Abdullah Çırakoğlu1, Erdal Benli1
1Education and Research Hospital, Department of Urology, Ordu University, Ordu, Turkey.
Andrology
|July 14, 2023
概括
在排除其他原因后,这项研究没有发现维生素B12 (vit B12) 水平与男性勃起功能障碍 (ED) 之间的显著联系. 需要进一步的研究才能充分理解维生素B12和ED之间的关系.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 内分泌学 在内分泌学.
- 营养科学 营养科学
背景情况:
- 勃起功能障碍 (ED) 是一种影响性健康的常见疾病,具有多因素的病因.
- 了解特定营养素,如维生素B12在ED中的作用,对于全面的患者护理至关重要.
研究的目的:
- 调查血清维生素B12 (vit B12) 水平与勃起功能障碍 (ED) 之间的相关性.
- 在精心挑选的一组男性患者中评估这种关系,不包括其他已知易发性障碍的诱导因素.
主要方法:
- 包括一个由136名男性患者组成的队列,这些患者在2015年至2022年期间参加了泌尿外科诊所.
- 患者根据血清维生素B12水平 (低≤200 mg/dL与正常) 进行分类. 使用男性-5 (SHIM-5) 性健康库存评估勃起功能.
- 排除标准很严格,排除了可能影响ED的并发性疾病,药物使用或手术病史的患者.
主要成果:
- 在低维生素B12水平和正常水平 (p=0.575) 的患者之间没有观察到SHIM-5评分的统计学上显著差异.
- 在研究队列中的23.5%人群中发现了维生素B12缺乏.
- 在维生素B12水平和性欲障碍的存在之间没有发现显著的关联.
结论:
- 这项研究没有发现血清维生素B12水平与男性勃起功能障碍之间存在显著的相关性,这与一些现有的文献相反.
- 需要进一步的精心设计的前性随机受控研究来阐明维生素B12和ED之间的复杂关系.
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