在人类牙细胞中,P38α 促进了 TNF-α 诱导的 IL-8 生产

Dan Mao1, Hiroshi Inoue2, Takuya Notomi3,4

  • 1Graduate School of Dentistry, Department of Physiology, Osaka Dental University, Osaka, Japan.

PubMed
概括

瘤坏死因子-α (TNF-α) 激活了牙细胞中的p38信号,增加了互白素-8 (IL-8) 的产生. 对于这种炎症反应来说,p38α异型是至关重要的,为牙周病治疗提供了潜在的点.

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