移动剂量对重症中风患者出院处置的影响
Nicole Mazwi1, India Lissak2, Karuna Wongtangman3,4
1Department of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA.
概括
在中风患者的重症监护室 (ICU) 进行早期和密集的动员,可显著降低不良出院. 更高的动员剂量与更好的患者结果相关,这表明中风后早期体力活动的关键作用.
科学领域:
- 神经学 神经学
- 密集护理医学 密集护理医学
- 物理疗法物理治疗
背景情况:
- 在重症监护室 (ICU) 的动员有望改善中风患者的治疗结果.
- 在ICU中卒中患者的最佳动员策略尚未明确.
研究的目的:
- 确定动员剂量在ICU对中风患者不良出院处置的影响.
主要方法:
- 一项国际,前性,观察性队列研究,涉及重症中风患者.
- 每天使用动员量化得分 (MQS) 量化动员.
- 包括功能独立的成年人,在中风发作后48小时内被送往重症监护室.
主要成果:
- 高剂量调动 (平均MQS>7.3) 与不良排泄的可能性显著降低有关 (aOR:0.14;95%CI:0.06-0.31).
- 动员剂量在各中心和患者之间有很大差异,而不依赖于并发症或疾病严重程度.
- 最终分析包括了162名患者.
结论:
- 在急性ICU环境中增加动员可能会改善中风后的患者康复和结果.
- 早期和密集的动员方案可能有利于在重症监护中的中风幸存者.
相关概念视频
Discharge Summary Forms
784
The discharge summary is crucial as it enables a smooth transition from a healthcare facility to a patient's home or another care setting. This critical document facilitates seamless continuity of care, ensuring patients receive the necessary support and attention.
Here's a detailed look at the key components and guidelines for preparing a discharge summary:
Here's a detailed look at the key components and guidelines for preparing a discharge summary:
784
Compartment Models: Two-Compartment Model
5.7K
The two-compartment model divides the body into central and peripheral compartments to account for varying blood perfusion rates among organs and tissues, affecting drug distribution. The central compartment includes blood and highly perfused tissues with rapid drug distribution, while the peripheral compartment contains tissues with slower drug distribution. After a single IV bolus dose, the drug concentration is high in plasma and low in tissues. The drug distribution between compartments...
5.7K
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
12
Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
12
Acute Coronary Syndrome IV: Interprofessional Care
12
IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
12
Rational Dosage Regimen: Maintenance Dose and Loading Dose
4.2K
A rational dosage regimen considers a drug's pharmacokinetics, including its absorption, distribution, metabolism, and elimination from the body. By understanding these factors, the appropriate dosage can be determined, and the dosing schedule can be designed to achieve and maintain the desired therapeutic effect while minimizing adverse effects.
In most cases, drugs are administered repetitively or infused continuously to maintain a steady-state concentration in the body. At a steady...
In most cases, drugs are administered repetitively or infused continuously to maintain a steady-state concentration in the body. At a steady...
4.2K
Drug Distribution: Volume of Distribution
5.2K
The volume of distribution refers to the theoretical volume necessary to contain the entire amount of an administered drug at the same concentration observed in the blood plasma. The body's intracellular fluid compartment, which makes up two-thirds of the total body water, is contrasted with the extracellular fluid compartment—comprising plasma and interstitial fluid—that accounts for one-third. The volume of distribution can vary depending on the characteristics of the drug.
5.2K


