致命的胃肠道疾病由于COVID-19:一个案例系列
Junya Hagiwara1, Naofumi Bunya1, Keisuke Harada1
1Intensive Care Unit, Sapporo Medical University, Sapporo, JPN.
Cureus
|July 14, 2023
概括
冠状病毒疾病2019 (COVID-19) 可以导致致命的胃肠道 (GI) 疾病,呈现为严重的腹. 这些严重的胃肠道并发症,类似于胃肠道移植与宿主疾病,可以导致多个器官衰竭和死亡.
科学领域:
- 胃肠病学 胃肠病学
- 传染性疾病 传染性疾病
- 关键护理医学 关键护理医学
背景情况:
- 冠状病毒疾病2019 (COVID-19) 通常会出现呼吸系统症状,呼吸系统衰竭是导致死亡的主要原因.
- 胃肠道 (GI) 症状在COVID-19中也被发现,但严重的,致命的GI并发症很少被报告.
研究的目的:
- 报告和描述COVID-19感染后发生的三起致命胃肠道疾病病例.
- 调查COVID-19诱导的肠道病理和肠道移植与宿主疾病 (GI-GVHD) 之间的潜在相似之处.
主要方法:
- 三名患有严重COVID-19肺炎的患者的病例系列需要机械通风和V-V ECMO.
- 临床评估包括CT扫描,内镜和胃肠道组织的病理检查.
- 临床过程,治疗干预措施和结果的分析.
主要成果:
- 这三名患者在最初的呼吸改善后都出现了严重的,耐火的水性腹.
- 病理发现与GI-GVHD有相似之处.
- 尽管在重症监护中,所有患者都死于多个器官衰竭,而败血症是由于肠道粘膜破坏引起的.
结论:
- COVID-19可能会导致严重的,致命的胃肠道疾病.
- 在这些情况下,胃肠道病理与GI-GVHD有共同的特征.
- 需要进一步的研究来阐明COVID-19中严重的胃肠道并发症的机制和临床影响.
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