技术基础设施的指导原则,以支持可计算的生物医学知识
Jamie McCusker1, Leslie D McIntosh2,3, Chris Shaffer4
1Rensselaer Polytechnic Institute Computer Science Troy New York USA.
本研究概述了开发可计算生物医学知识 (CBK) 基础设施的关键原则. 它强调互操作性,值得信赖的代表性和开放标准,以促进医疗保健知识的可访问性和可用性.
科学领域:
- 生物医学信息学 生物医学信息学
- 卫生系统科学 卫生系统科学
- 知识管理知识管理
背景情况:
- 动员可计算生物医学知识工作组确定了需要强大的基础设施来利用可计算生物医学知识 (CBK).
- 现有的系统往往难以弥合原始数据和可操作,可计算的知识之间的差距.
- 学习健康系统和FAIR原则的整合对于有效的知识翻译至关重要.
研究的目的:
- 构思并为必要的CBK基础设施奠定基础.
- 要区分可计算的知识和数据.
- 为推进CBK基础设施发展提出指导原则.
主要方法:
- 工作组调查结果的概念化和总结.
- 在学习健康系统和FAIR原则中的上下文化.
- 制定CBK基础设施发展的三个核心原则.
主要成果:
- 定义了可计算的知识和数据之间的区别.
- 在更广泛的医疗保健和数据管理框架内对CBK基础设施进行了上下文化.
- 提出了三个指导原则:互操作性,稳定/值得信赖的表示和开放性.
结论:
- 推进CBK基础设施需要促进可查找,可访问,可互操作和可重复使用 (FAIR) 数据和知识的互操作系统.
- 稳定,可靠,人文和机器可读的知识表示是必不可少的.
- 可计算知识资源和支持标准的开放性对于广泛采用和影响至关重要.
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