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磁共振成像功能是否在不同种族和种族的多发性硬化症患者之间有所不同?
Nabeela Nathoo1, Burcu Zeydan1,2, Nur Neyal1,2
1Division of Multiple Sclerosis and Autoimmune Neurology, Department of Neurology, Mayo Clinic, Rochester, MN, United States.
Frontiers in neurology
|July 14, 2023
概括
多发性硬化症 (MS) 在非洲裔美国人和拉丁美洲人群中似乎更严重. 本综述检查了不同群体的MRI发现,以了解疾病表现和潜在的差异.
科学领域:
- 神经学 神经学
- 放射学 放射学是一门学科.
- 免疫学 免疫学 免疫学
背景情况:
- 多发性硬化症 (MS) 在种族和民族群体中表现出不同的临床严重程度和放射性负担.
- 与白人相比,患有多发性硬化症的非裔美国人往往呈现出更严重的疾病和更具攻击性的成像发现.
研究的目的:
- 审查磁共振成像 (MRI) 研究,检查多种多发性硬化患者的病变负担,炎症和神经退行.
- 讨论可能导致MS中观察到的种族和种族差异的非生物因素.
- 突出未来研究的领域,以了解多发性硬化病原和进展的根本差异.
主要方法:
- 对成人和患有多发性硬化症的儿科患者的MRI研究进行系统审查.
- 对成像数据的分析,重点关注病变负载,炎症标志物,神经退行性变化和治疗反应.
- 讨论可能影响MS呈现的社会环境和生物因素.
主要成果:
- 有证据表明,在患有MS的非裔美国人中,放射性疾病负担更为激烈.
- 在不同种族和民族群体中观察到病变负担,炎症和神经退行变化的变化.
- 对疾病修饰疗法的成像反应在不同人群中可能有所不同.
结论:
- 在MS临床表现和放射学发现中,种族和种族差异是显而易见的.
- 了解这些差异需要研究超越生物因素,包括社会环境影响.
- 进一步的研究至关重要,以阐明这些差异背后的机制,并为公平的护理提供信息.
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