高强度间歇训练对多样化的癌症幸存者群体的影响:CAPABLE,一个试点研究
Jennifer L Beebe-Dimmer1,2, David G Finlay2, Julie J Ruterbusch1,2
1Wayne State University, School of Medicine Departments of Oncology, Detroit, MI 48201, United States.
Preventive medicine reports
|July 14, 2023
概括
高强度间歇训练改善了癌症幸存者的身体组成,HbA1c和生活质量. 这种运动干预表明,它有望提高生存率并减少健康差异.
科学领域:
- 运动科学 运动科学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 美国癌症协会的指导方针建议癌症幸存者每周进行150分钟的中度至强度体力活动.
- 很少有癌症幸存者符合这些运动建议,特别是少数群体.
- 坚持运动对于改善癌症幸存者的长期健康结果至关重要.
研究的目的:
- 评估12周高强度间歇和力量训练计划对癌症幸存者的影响.
- 评估体重,体脂百分比,心脏代谢标志物和与健康相关的生活质量 (HRQoL) 的变化.
- 在试点研究中探索密集炼干预的可行性.
主要方法:
- 在CAPABLE研究中,48名癌症幸存者参加了为期12周的单臂试点炼干预.
- 参与者每周三天进行高强度间歇训练 (HIIT) 和力量训练.
- 测量身体组成,血清标志物 (包括HbA1c) 和HRQoL在基线和计划完成时进行了评估.
- 配对的t测试被用来分析结果措施的变化.
主要成果:
- 在12周内,体重,体重指数和身体脂肪百分比有显著的减少.
- 糖化血红蛋白 (HbA1c) 水平下降,表明心脏代谢健康状况有所改善.
- 在整体HRQoL及其个别领域 (身体,社会,情绪,功能) 报告了临床上有意义的改善.
结论:
- 一个为期12周的高强度间歇训练计划导致癌症幸存者的身体组成,HbA1c和生活质量显著改善.
- 这些发现表明,强烈运动干预可以积极影响生存率.
- 未来的研究应该包括一个对照组,并调查参与和坚持的障碍,以优化干预的有效性和解决健康差异.
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