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Updated: Jul 23, 2025

Isolation and Th17 Differentiation of Naïve CD4 T Lymphocytes
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Published on: September 26, 2013

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调节IL-17骨干动力学降低了受体亲和力,并揭示了一个新的抑制机制

Daniel J Shaw1, Lorna C Waters2, Sarah L Strong2

  • 1Department of Chemistry and York Biomedical Research Institute, University of York Heslington York YO19 5DD UK neil.hunt@york.ac.uk.

Chemical science
|July 14, 2023
PubMed
概括

蛋白质的灵活性决定了细胞因子受体结合的亲和力. 小分子可以通过固蛋白质来抑制这种相互作用,为牛皮等自身免疫性疾病提供新的治疗策略.

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