卡尔佩可以通过降低干扰素调节因子1的调节来逆转与香烟烟雾暴露相关的过敏性鼻炎的葡萄糖皮质体抗性

Wen-Xuan Zhu1, Yang Xi1, Fen Li2

  • 1Department of Otolaryngology, Head and Neck Surgery, Renmin Hospital of Wuhan University, Wuhan, PR China.

Heliyon
|July 14, 2023
PubMed
概括

香烟烟雾通过改变DNA甲基转移酶3a (Dnmt3a) 和干扰素调节因子1 (IRF1) 的表达来加剧过敏性鼻炎 (AR) 和葡萄糖皮质激素耐药性. 卡尔佩丁治疗抑制IRF1,有效治疗这种疾病.

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