转录组分析确定了I类组素脱乙酶在阿尔茨海默氏症疾病中的作用

Fan Geng1, Na Zhao1, Xiu Chen1

  • 1School of Medicine, Southeast University, Nanjing, 210009, China.

Heliyon
|July 14, 2023
PubMed
概括

表观遗传修饰,特别是I类组素脱乙酶 (HDACs),影响阿尔茨海默病 (AD) 脑基因表达. HDAC1和HDAC8在阿尔茨海默病中表达的增加,表明它们作为诊断生物标志物的潜力.

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