相关实验视频

Updated: Jul 23, 2025

A Non-random Mouse Model for Pharmacological Reactivation of Mecp2 on the Inactive X Chromosome
08:27

A Non-random Mouse Model for Pharmacological Reactivation of Mecp2 on the Inactive X Chromosome

Published on: May 22, 2019

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逃脱但不活跃的X链蛋白复杂编码基因可以实现X染色体剂量补偿,并成为X染色体不活化相关疾病的基础

Zhihao Xing1,2, Yuchao Zhang2, Zhongyuan Tian3

  • 1Clinical Laboratory, Institute of Pediatrics, Shenzhen Children's' Hospital, Shenzhen, China.

Heliyon
|July 14, 2023
PubMed
概括

X染色体剂量补偿实现了基因表达等价性. 活跃X染色体上的脱离蛋白质复合基因 (EsP) 显示出更高的表达,这表明它们驱动了这个过程,可能与疾病有关.

关键词:
自身免疫性疾病是一种自身免疫性疾病.剂量敏感性 剂量敏感性心理发展 心理发展SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1 SP1在XCI逃跑者.

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