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Updated: Jul 23, 2025

Studying the Effects of Tumor-Secreted Paracrine Ligands on Macrophage Activation using Co-Culture with Permeable Membrane Supports
07:44

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巨细胞IL-1β通过膜AIM2炎症酶激活在瘤微环境中促进瘤发生

Zhi Huan Chew1,2,3,4, Jianzhou Cui1,2,3, Karishma Sachaphibulkij1,2,3

  • 1Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Frontiers in immunology
|July 14, 2023
PubMed
概括

瘤核酸激活巨细胞,触发炎症酶反应,促进癌症的生长. DNA-RNA混合体是AIM2炎症酶的强有力的激活剂,提供潜在的治疗点.

关键词:
在AIM2炎症酶中,AIM2炎症细胞质DNA是细胞质DNA.一些炎症一些炎症这是先天免疫力.瘤微环境是一个微环境.

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