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运动员高风险心血管疾病查的质量-系统性审查
Nicole M Panhuyzen-Goedkoop1,2, André L M Verbeek3, René J Goedkoop4
1Department of Cardiology, Amsterdam University Medical Centers, Heart Centre, Amsterdam, The Netherlands.
Scandinavian journal of medicine & science in sports
|July 14, 2023
概括
运动员突然心脏死亡查的证据质量非常低,有效性不清楚. 高风险心血管疾病的患病率很低,错误阳性率很高,需要谨慎的建议.
科学领域:
- 心脏病学 心脏病学
- 运动医学 运动医学
- 公共卫生 公共卫生
背景情况:
- 突然心脏死亡 (SCD) 是运动员死亡的主要原因.
- 建议对高风险心血管疾病 (HRCC) 进行查,以预防SCD.
- 目前的查策略缺乏可靠的证据,其有效性尚不清楚.
研究的目的:
- 系统地审查运动员查的方法质量和证据质量.
- 评估查策略在运动员中检测HRCC的有效性.
主要方法:
- 在Medline,Embase,Scopus和Cochrane图书馆进行系统的文献搜索,截至2021年6月.
- 包括关于运动员心血管查,策略细节,测试结果和HRCC检测的原始数据的文章.
- 评估方法质量 (QUADAS-2),证据质量 (GRADE) 和查有效性 (SWiM).
主要成果:
- 包括33篇文章 (1991-2018) 涉及82,417名运动员.
- 由于研究设计和报告的局限性,方法质量和证据质量被评为"非常低".
- 查疗效无法可靠地确定;HRCC的患病率为0.43%,假阳性率为13.0%.
结论:
- 运动员查的方法质量和证据质量不足于最佳.
- 目前对运动员HRCC的查方法的有效性仍然没有得到证实.
- 低HRCC患病率和高假阳性率需要谨慎的个人建议.
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