儿童嗅觉功能障碍:一个范围审查
Jennifer Eva Payandeh1, Mehras Motamed1, Keshinisuthan Kirubalingam1
1Faculty of Medicine, Queen's University, Kingston, Ontario, Canada.
概括
儿科嗅觉功能障碍源于45个已确定的原因,包括先天性和获得性. 临床医生需要诊断方法,安全教育至关重要,当原因仍然未知.
科学领域:
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 儿科医学 儿科医学
- 神经科学是一个神经科学.
背景情况:
- 嗅觉障碍在成年人中得到了广泛的研究,但对儿科嗅觉功能障碍的研究有限.
- 了解儿童嗅觉丧失的原因和管理对于他们的发展和安全至关重要.
研究的目的:
- 确定儿科患者嗅觉丧失的已知原因.
- 评估儿童嗅觉测试的利用性和有效性.
- 总结当前治疗儿科嗅觉功能障碍的治疗策略.
主要方法:
- 2020年9月对PubMed,Ovid MEDLINE和Web of Science数据库进行了系统范围审查.
- 两个独立的审稿人根据预定义的包含/排除标准对标题,摘要和全文进行了选.
- 提取的数据包括研究特征,参与者人口统计,嗅觉功能障碍证据,嗅觉测试细节,病因和治疗方法.
主要成果:
- 最终分析包括了103篇涉及1654名参与者的文章.
- 宾夕法尼亚大学的气味识别测试是最常见的气味评估工具 (占研究的21%).
- 总共有45种原因被确定:22种先天性和23种获得性嗅觉功能障碍.
结论:
- 儿科嗅觉功能障碍具有不同的病因,需要临床医生的结构化诊断方法.
- 只有很少的特定疗法被确定,通常是根据潜在原因量身定制的.
- 当病因不明确时,患者和护理人员对与嗅觉丧失相关的安全性教育至关重要.
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