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Updated: Jun 26, 2026

Expansion of Human Peripheral Blood γδ T Cells using Zoledronate
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丹诺苏马布在巨细胞丰富的骨瘤中:一项开放式多中心二期研究

Astrid Lipplaa1, Willem H Schreuder2,3,4, Sarina E C Pichardo5

  • 1Medical Oncology, Leiden University Medical Center, Leiden, The Netherlands.

The oncologist
|July 14, 2023
PubMed
概括

德诺苏马布在治疗巨细胞丰富骨瘤 (GCRTB) 中表现出潜力,观察到骨化改善. 然而,由于新出现的数据,该研究被停止了,使得denosumab在这个适用症上没有得到支持.

关键词:
动脉瘤骨囊 动脉瘤骨囊这里没有denosumab.巨细胞颗粒瘤巨细胞颗粒瘤骨的巨细胞丰富瘤的骨.系统性治疗是一种全身疗法.

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Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...