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在COVID-19的三个主要变异中,COVID-19后动脉血栓事件是COVID-19的三大变异之一
Sudhir Bhandari1, Shashank Joshi2, Govind Rankawat3
1Vice Chancellor, RUHS and Professor Emeritus, Department of General Medicine, SMS Medical College, Jaipur, Rajasthan; Corresponding Author.
The Journal of the Association of Physicians of India
|July 14, 2023
概括
与Omicron和Alpha变种相比,COVID-19的Delta变种对COVID后血栓事件的风险更高. 血栓事件的风险与疾病的严重程度相关.
科学领域:
- 心血管研究研究心血管研究
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,COVID-19后的血栓事件仍然是严重的健康负担.
- 了解这些事件的变异特异性风险至关重要,特别是随着SARS-CoV-2正在进行的演变.
- 虽然疫苗接种减少了严重的COVID-19,但之前感染的剩余风险仍然存在.
研究的目的:
- 调查不同严重急性呼吸综合征冠状病毒2 (SARS-CoV-2) 变种中COVID-19后血栓事件的发生率和特征.
- 为了比较感染Alpha,Delta和Omicron变种后发生的血栓事件的风险.
- 确定疾病严重程度,患者人口统计和COVID-19后血栓事件的发展之间的关系.
主要方法:
- 这是一项前性观察性研究,涉及3220名感染Alpha,Delta或Omicron变种的COVID-19患者.
- 数据收集包括人口统计,临床资料,并发症,疾病严重程度和疫苗接种情况.
- 患者被跟踪了六个月,以确定和分析COVID-19后的血栓事件.
主要成果:
- 总体而言,7.48%的患者发生了COVID-19后的血栓事件,在Delta变种组 (14.90%) 的发病率最高.
- 冠状动脉疾病和脑血管疾病是观察到的最常见的血栓事件.
- 患有中度至重度COVID-19的患者患有血栓事件的风险显著更高,并且因变体而异,其中三角形呈现最高风险.
结论:
- 感染Delta变种的患者面临更高的COVID-19后血栓事件的风险.
- 欧米克朗变种呈现的风险最低,而阿尔法变种呈现的风险中等.
- 最初的COVID-19疾病的严重程度是影响COVID-19后血栓事件发生的可能性的关键因素.
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