以METTL3为媒介的m6A修改pri-miR-148a-3p通过调节TXNIP影响前列腺癌的进展

Guoqiang Li1, Junwen Liu2, Yinhuai Wang1

  • 1Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, China.

PubMed
概括

甲基转移酶样3 (METTL3) 通过通过m6A修饰对miR-148a-3p进行上调,从而促进前列腺癌 (PCa),从而使TXNIP沉默. 干扰METTL3可以抑制PCa的进展和瘤的生长.

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