儿童和青少年脂肪和肌肉发育之间的相互作用
Leonie Schafmeyer1,2, Tobias Linden2, Heidrun Lioba Wunram3
1University of Cologne, Medical Faculty and University Hospital, Center of Prevention and Rehabilitation, UniReha, Lindenburger Allee 44, 50931 Cologne, Germany Leonie Schafmeyer ORCID ID https://orcid.org/0000-0001-6704-7266 Ibrahim Duran ORCID ID https://orcid.org/0000-0003-4044-8822.
概括
肥胖症正在上升,但其与年轻人肌肉质量的联系尚不清楚. 这项研究发现,在调整了关键因素后,儿童和青少年的脂肪质量和骨肌肉质量之间存在负相关性.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 身体组成分析 身体成分分析
- 肥胖问题研究研究
背景情况:
- 全球肥胖率的上升需要了解相关的身体组成变化.
- 在儿童群体中,多余脂肪质量和骨肌肉质量之间的关系仍未得到充分研究.
研究的目的:
- 调查儿童和青少年的脂肪质量和肌肉质量之间的联系.
- 为了调整包括体重,年龄,身高,性别,种族和身体活动在内的混因素.
主要方法:
- 来自NHANES 1999-2004数据集 (8-20岁) 的849个全身DXA扫描的分析.
- 尾瘦体质量 (appLBM) 用作肌肉质量的代理.
- 统计方法包括双变量分析,多重线性回归和调解分析.
主要成果:
- 最初观察到脂肪质量和尾性瘦体质量 (r=0.336) 之间存在正相关性.
- 多重回归分析显示,在控制体重 (-0.517) 时,脂肪质量和尾性瘦体质量之间存在负相关性.
结论:
- 在儿童和青少年中,脂肪质量和骨肌肉质量之间存在显著的负相关性.
- 需要进一步的研究来探索脂肪和肌肉细胞之间的潜在生化相互作用.
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