在COVID-19后的年轻男性中,自主调节,自发的巴罗反射敏感性和疲劳
P L Latchman1, Q Yang, D Morgenthaler
1Southern Connecticut State University, New Haven, Connecticut, U.S.A. latchmanp1@southernct.edu.
Physiological research
|July 14, 2023
概括
与对照人群相比,从COVID-19中恢复过来的年轻男性在自主调节或巴罗反射灵敏度 (BRS) 中没有显著差异. 疲劳与这些心血管风险因素在感染后没有联系.
科学领域:
- 心血管生理学心血管生理学
- 自主神经系统功能 自主神经系统功能
- 传染病研究 传染病研究
背景情况:
- COVID-19可能会损害自主调节和巴罗反射灵敏度 (BRS),可能导致不良的心血管结果.
- 在COVID-19期间和之后观察到自主功能障碍和疲劳,但COVID-19后疲劳和自主功能受损之间的联系仍然不清楚.
- 年轻男性可能面临未被检测到的心血管风险,如果自主功能障碍在COVID-19后持续存在.
研究的目的:
- 为了比较副交感和交感调制,以及COVID-19后年轻男性的BRS与对照.
- 为了调查疲劳是否与COVID-19后年轻男性的自主调节和BRS受损有关.
主要方法:
- 通过功率光谱密度分析测量了副交感调制 (lnHFR-R),交感调制 (LFSBP) 和BRS (-指数).
- 在一组20名患有COVID-19的年轻男子和24名健康对照者之间比较这些自主和BRS变量.
- 统计分析包括独立的t测试和曼-惠特尼U测试.
主要成果:
- 在lnHFR-R (P=0.20),LFSBP (P=0.11) 或BRS-index (P=0.20) 中,没有发现COVID-19和对照组之间的显著差异.
- 在研究群体中,没有发现疲劳与自主调节或BRS受损有关.
- 结果表明,与对照人群相比,在COVID-19后的年轻男性中,自主调节或BRS没有可检测的差异.
结论:
- 与健康同龄人相比,年轻男性在COVID-19后的自主调节或BRS中没有显著差异.
- 疲劳似乎不是一个可靠的指标,自主功能受损或BRS在后COVID-19年轻人.
- 研究结果表明,由于COVID-19相关的dysautonomia或受损的BRS,年轻男性可能不会面临高心血管风险.
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