全球纵向应变的悖论性增加通过手握运动,尽管左心室透静功能障碍
Ko Motoi1, Hiroyuki Iwano2,3, Suguru Ishizaka1
1Department of Cardiovascular Medicine, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, Sapporo, Japan.
Echocardiography (Mount Kisco, N.Y.)
|July 14, 2023
概括
在手握运动期间的全球纵向应变 (GLS) 变化揭示了心肌功能障碍. 先进的扩张性功能障碍,而不是GLS降低,与心血管患者GLS增加有关.
科学领域:
- 心脏病学 心脏病学
- 心声回声图 (Echocardiography) 是一种心声回声图.
- 心肌机械学的心肌机械学
背景情况:
- 全球纵向应变 (GLS) 是左心室 (LV) 功能障碍的敏感指标.
- 后载对GLS的影响是一个公认的因素.
- 这项研究研究了GLS对握手运动的反应,以评估内在心肌功能.
研究的目的:
- 评估手握运动期间GLS的下降是否比先前确定的更为敏感的内在心肌功能障碍标志物.
- 探索手握运动诱导的GLS变化与左心室 (LV) 扩张功能之间的关系.
- 在心血管疾病患者的手握运动中调查影响GLS变化的因素.
主要方法:
- 在90名心血管疾病患者中进行了手握运动压力回声心电图,并保留了LV喷射分数.
- 测量了透析壁应力 (DWS),左心房 (LA) 体积指数与早期透析心房环状速度 (LAVI/a') 比率,以及LA菌株.
- 显著的GLS变化被测试-重新测试变异性 (2.65%) 定义.
主要成果:
- 平均GLS与运动没有显著变化,但发生了实质性的个体变化 (减少,不变,增加).
- 患有GLS增加的患者表现为晚期LV透静功能障碍和心率响应减弱.
- 扩张性壁压力,左心房增压和II级+扩张性功能障碍预测了GLS的增加.
结论:
- 与假设相反,随着手握运动增加的GLS与保留LV喷射分数的患者的晚期LV透析功能障碍有关.
- 握手运动对后负荷的影响在心力衰竭患者中不均,导致可变的GLS变化.
- 对手握炼的GLS反应可能会为复杂的心肌和扩张功能相互作用提供见解.
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