在移植后,尿导管的提前或晚期切除
Michael Goodfellow1, Emily R Thompson1, Samuel J Tingle1
1Institute of Transplantation, The Freeman Hospital, Newcastle upon Tyne, UK.
The Cochrane database of systematic reviews
|July 14, 2023
概括
移植后的早期与晚期尿导管切除没有明显的益处. 需要更多高质量的研究来确定减少尿路感染 (UTI) 和并发症的最佳时间.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 移植手术 移植手术
- 传染性疾病 传染性疾病
背景情况:
- 移植是对末期病的最佳治疗方法.
- 手术后的尿路导管治疗有助于愈合,但存在尿路感染 (UTI) 的风险.
- 移植后取出导管的最佳时间尚不清楚,这可能会影响尿路感染和并发症的发生率.
研究的目的:
- 为了比较早期 (<5天) 和晚期 (≥5天) 尿导管切除移植后的结果.
- 主要结局包括有症状的尿路感染,无症状的细菌性尿病和主要的泌尿器官并发症.
- 评估导管切除时间对患者康复的影响.
主要方法:
- 随机对照试验 (RCT) 和准RCT的系统审查.
- 搜索了Cochrane脏和移植注册表,CENTRAL,MEDLINE,EMBASE,ICTRP和clinicalTrials.gov.gov. 这些网站.
- 包括所有捐赠者类型和接受者人口统计数据;评估偏差风险并使用GRADE来确定证据.
主要成果:
- 包括两项涉及197名患者的研究;两者都有高或不清楚的偏差风险.
- 早期和晚期去除无症状细菌性尿症之间没有显著差异 (RR 0.89,95% CI 0.17-4.57;非常低的确定性证据).
- 关于尿路感染和泌尿系统并发症的数据缺乏;随访时间仅限于一个月.
结论:
- 没有足够的证据来支持移植后的早期和晚期导管切除.
- 目前的研究质量不佳,需要高质量的RCT.
- 需要进一步的研究,以建立最佳的导管管道管理策略,以尽量减少风险.
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