一种新的原发性骨质疏松症查工具 (POST) 用于50岁及以上的成年人
Yuchen Tang1,2,3, Jinmin Liu1,2,3, Cong Tian1,2,3
1Department of Orthopaedics, Lanzhou University Second Hospital, Lanzhou, Gansu, China.
Endocrine
|July 14, 2023
概括
一种新的骨质疏松症查工具 (POST) 有效地识别了50岁及以上的患骨质疏松症风险的个人. 这种简单的工具显示出高灵敏度,可能有助于未来的骨质疏松症查工作.
科学领域:
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
- 医学诊断 医学诊断 医学诊断
背景情况:
- 骨质疏松症对50岁及以上的成年人构成重大健康风险.
- 有效的查工具对于早期检测和干预至关重要.
- 现有的选方法可能在可访问性或准确性方面存在局限性.
研究的目的:
- 开发和验证一个简单的原发性骨质疏松症查工具 (POST).
- 评估POST在识别50岁及以上成年人骨质疏松症方面的有效性.
- 为了比较POST与骨质疏松自我评估工具 (OST) 的性能.
主要方法:
- 利用来自50岁以上成年人的国家健康和营养检查调查 (NHANES) 的数据.
- 根据骨矿物密度 (BMD) 值来定义骨质疏松症.
- 使用已确定的方法开发POST,并使用接收器操作特征 (ROC) 曲线和曲线下的面积 (AUC) 分析性能.
主要成果:
- 在开发和验证队列中,POST的AUC值为0.81.
- 确定了≥7的最佳POST得分值,达到90%以上的灵敏度.
- 与OST相比,POST表现出显著更高的灵敏度,在中国人口子组中显示AUC为0.75.
结论:
- POST是一种方便且有效的工具,用于对50岁及以上的成年人进行骨质疏松症查.
- 该工具为未来的骨质疏松症查策略提供了宝贵的方法进步.
- POST的高灵敏度支持其在识别需要进一步诊断评估的个体中的实用性.
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