肝功能对预测患有严重大动脉狭窄和减少射出小部分的患者的死亡率的影响是什么?
Sevgi Özcan1, Esra Dönmez1, İrfan Şahin1
1Department of Cardiology, Bağcılar Training and Research Hospital, İstanbul, Türkiye.
概括
较高的白蛋白-白素得分表明肝功能不佳,并且与患有严重症状性大动脉狭窄和经过TAVI的减少射出分数的患者的死亡率增加有关. 这一分数有助于对这些高风险患者的风险分层.
科学领域:
- 心脏病学 心脏病学
- 肝病学 肝病学是一种肝病学.
- 跨导管大动脉植入 (TAVI) 的方法
背景情况:
- 肝功能障碍是严重的症状性大动脉狭窄和减少射出分数的患者的担忧.
- 专白素 (ALBI) 评分评估了肝功能储备.
- 在这个患者群体中,评估ALBI得分的预后价值至关重要.
研究的目的:
- 评估ALBI得分对死亡率和再入院的预后影响.
- 为了确定ALBI评分是否预测严重的症状性大动脉狭窄症患者的结果,患者的射出分数减少,接受TAVI.
主要方法:
- 在2013-2021年期间住院的77名患者的回顾性研究.
- 使用手术前胆红素和白蛋白水平计算的ALBI得分.
- 主要结局:30天和1年的全因死亡率,以及1年的心力衰竭住院治疗.
主要成果:
- 高ALBI评分 (>-2.25) 与显著更高的30天 (50.0%对4.3%) 和1年死亡率 (80.0%对10.6%) 相关.
- 在高ALBI分数组 (86.7%与44.7%) 中,总体初级结局显著更高.
- 两组之间在住院,并发症或重新住院的时间没有显著差异.
结论:
- 高ALBI分数是这种患者群体中死亡率的独立风险因素.
- 程序前的ALBI评分评估为风险分层提供了有价值的信息.
- ALBI评分有助于识别接受TAVI治疗的高风险患者,这些患者患有严重的症状性大动脉狭窄,射出率降低.
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