里托纳维尔回顾:融化结晶可以轻松找到晚出现的多态II,并意外发现新的多态III

Shuting Li1, Binbin Liu1, Ziqiao Chen1

  • 1School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.

PubMed
概括

在聚乙烯糖醇 (PEG) 的帮助下,融结晶有效地揭示了隐藏的药物多态,如Ritonavir (RIT) 形式II. 这种方法还发现了一种新的多态,Form III,对药物开发至关重要.

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