在Charcot-Marie-Tooth疾病中,手术纠正卡沃瓦鲁斯形
Glenn B Pfeffer1, Edward T Haupt
1From the Department of Orthopaedic Surgery, Cedars-Sinai Medical Center, Los Angeles, CA (Pfeffer), and the Department of Orthopaedic Surgery, Mayo Clinic Florida, Jacksonville, FL (Haupt).
概括
查尔科-玛丽-牙 (CMT) 病是一种遗传性神经病变,通常会导致可以通过手术治疗的足部形. 一些患者从膝盖以下的骨架中受益更多.
科学领域:
- 神经学 神经学
- 整形外科 整形外科 整形外科
- 遗传学 遗传学 是一个
背景情况:
- 查洛-玛丽-牙 (CMT) 是最常见的遗传性神经病变,影响运动和感觉神经.
- 它呈现出多样化的基因型,但相对统一的表型,主要有两种呈现.
- 渐进性足变形是CMT患者的一个关键的手术挑战.
研究的目的:
- 审查查科特-玛丽-图斯病的外科和非外科治疗策略.
- 突出及时干预对患者流动性和生活质量的影响.
- 根据临床表现和作者经验讨论治疗.
主要方法:
- 在Charcot-Marie-Tooth管理的文献综述.
- 对脚形的手术结果的分析.
- 对的正治疗的评估.
- 高级作者对临床经验的综合.
主要成果:
- 手术纠正cavovarus脚变形可以显著改善行走,减少疼痛,增加耐力.
- 早期的手术可以缓解关节性关节炎的进展.
- 接地反应脚脚架是患有分散下肢的患者的首选治疗方法.
结论:
- 手术管理为CMT患者带有足部形提供了改变生活的好处.
- 对于严重的患者来说,整形骨架管理至关重要.
- 个性化治疗策略对于优化夏科特-玛丽-图斯病的治疗结果至关重要.
相关概念视频
Disorders of the Skeletal Muscle
997
The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
997
Cystic Fibrosis: Management
195
Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
Sinus disease and chronic...
195
Bone Disorders
3.7K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.7K
Inflammatory Bowel Disease V: Surgical Management
171
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
171


