相关实验视频

Updated: Jul 23, 2025

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Evaluation of the Cognitive Performance of Hypertensive Patients with Silent Cerebrovascular Lesions

Published on: April 23, 2021

基于人口的研究中大脑小血管疾病:我们在看什么 - 什么不是?

Sanne S Mooldijk¹, M Arfan Ikram¹

¹Department of Epidemiology, Erasmus MC University Medical Center, Rotterdam, the Netherlands.

Aging and disease

|July 14, 2023

概括

大脑小血管疾病 (CSVD) 是认知能力下降的主要原因. 目前的方法很难完全捕捉CSVD.

科学领域:

神经学神经学
神经成像是一种神经成像.
血管生物学血管生物学

背景情况:

大脑小血管疾病 (CSVD) 是认知能力下降和痴呆的主要原因.
确切的病变发生和将CSVD与临床症状联系在一起的机制尚不清楚.
在体内对CSVD的量化很困难,阻碍了研究进展.

研究的目的:

审查目前评估CSVD的技术.
为了确定捕捉与CSVD相关的微血管变化的局限性.
突出CSVD评估需要改进的领域.

主要方法:

对现有的CSVD量化技术进行文献综述.
对CSVD目前的神经成像标记物的分析.
讨论CSVD中微血管的形态和功能方面.

主要成果:

现有的技术主要检测与CSVD相关的大脑异常.
目前的标记不充分反映了大脑微血管结构的动态形态和功能变化.
在充分量化CSVD对大脑健康的影响方面存在重大差距.

结论:

目前评估CSVD的方法在充分评估微血管病理方面存在局限性.
需要进一步的进展,以改善CSVD的体内量化.
更好的量化对于了解CSVD病原体和开发有效治疗方法至关重要.

更多相关视频

Reliable Isolation of Central Nervous System Microvessels Across Five Vertebrate Groups

Reliable Isolation of Central Nervous System Microvessels Across Five Vertebrate Groups

Published on: January 12, 2020

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Assessing Cortical Cerebral Microinfarcts on High Resolution MR Images

Published on: November 20, 2015

相关概念视频

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...