怀孕期间发生的自发性肺胸病在患有淋巴血管菌病的患者中
Aamir Munshi1, Alan D Hyslop2, Elizabeth J Kopras1
1Division of Pulmonary & Critical Care Medicine, University of Cincinnati, Cincinnati, OH, USA.
Respiratory investigation
|July 14, 2023
概括
淋巴管状菌病 (LAM) 患者的怀孕带有自发性肺胸病 (SPs) 的风险. 许多LAM诊断发生在怀孕期间,通常呈现为SPs,大多数事件发生在第二个三个月.
科学领域:
- 肺部医学 肺部医学
- 妇女健康 妇女健康
- 罕见疾病 罕见疾病
背景情况:
- 淋巴结核病 (Lymphangioleiomyomatosis,LAM) 是一种罕见的肺部疾病,主要影响女性.
- 患有LAM的患者具有自发性肺胸病 (SPs) 的风险增加.
- 怀孕对LAM患者的SP的影响还没有得到很好的描述.
研究的目的:
- 调查怀孕期间发生的自发性肺胸病 (SPs) 的发生率,时间和诊断含义,在患有淋巴血管菌病 (LAM) 的妇女中.
主要方法:
- 在被诊断为LAM的患者中进行了一项基于网络的调查.
- 调查数据收集了关于怀孕史,怀孕期间SPs发生情况和LAM诊断时间的信息.
- 50名受访者提供了数据,其中38人至少经历过一次怀孕.
主要成果:
- 在38名怀孕的LAM患者中,11名 (29%) 在怀孕期间至少经历过一次SP.
- 在38名孕妇中有13名 (34%),怀孕期间的呼吸道症状导致了LAM诊断,SPs是10名 (77%) 的初始表现.
- 大约60%的与怀孕相关的SPs发生在第二个三个月.
结论:
- 怀孕代表了在淋巴管状瘤 (LAM) 患者中自发性肺胸病 (SPs) 的重要时期.
- 怀孕期间的SPS可以导致LAM的早期诊断.
- 了解怀孕期间SPs的时间对于管理LAM患者至关重要.
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