精神病风险青少年的异常自我体验和神经认知功能:这两种脆弱性标志物之间仍然没有发现显著的关联
Caroline Ranem Mohn-Haugen1, Paul Møller2, Christine Mohn3
1Research Department, Vestre Viken Hospital Trust, 3004 Drammen, Norway; Department of Psychology, P. O. Box 1094 Blindern, University of Oslo, 0317, Oslo, Norway.
Comprehensive psychiatry
|July 14, 2023
概括
异常自我体验 (ASE) 和神经认知障碍在风险青少年中没有显著的关联. 这些不同的领域可能独立地导致精神病脆弱性,这表明需要更广泛的评估标准来预测发育轨迹.
科学领域:
- 精神病学是一个精神病学.
- 神经科学是一个神经科学.
- 发展心理学 发展心理学
背景情况:
- 异常自我体验 (ASE) 和神经认知障碍是精神病障碍的关键脆弱性标志物.
- 有限的研究探讨了精神病风险人群中ASE和神经认知之间的联系.
- 这项研究通过检查这些领域的非寻求帮助的青少年,临床上患精神病的高风险来弥补一个差距.
研究的目的:
- 调查异常自我体验 (ASE) 与精神病风险青少年的神经认知功能之间的关联.
- 为了澄清这两个基本领域的脆弱性之间的关系,在一个年轻的,处于风险的人群.
主要方法:
- 这项研究利用了挪威母亲,父亲和儿童队列研究 (MoBa) 的数据.
- 参与者包括48名青少年 (94%女性,平均年龄15.3岁),根据精神病和ASE项目的高得分被确定为有风险.
- 使用 MATRICS 共识认知电池评估神经认知功能,并通过总分数量化 ASEs.
主要成果:
- 回归分析显示,ASEs与任何评估的神经认知领域之间没有显著的关系.
- 这表明ASEs和神经认知功能可能在这个有风险的青少年队列中独立运作.
结论:
- 在不寻求帮助的,处于危险状态的青少年中,ASEs和神经认知功能之间没有发现显著的关联.
- ASEs和神经认知功能可能代表在危险状态下存在的不同,共存的脆弱性领域.
- 建议使用包括这两个领域在内的更广泛的评估范围,以更好地预测精神病的发展和了解早期的精神病理学.
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