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爱斯坦-巴尔病毒和遗传风险变异作为T-bet+ B细胞驱动的自身免疫疾病的决定因素

Laurens Bogers1, Kirsten L Kuiper1, Joost Smolders2

  • 1MS Center ErasMS, Department of Immunology, Erasmus MC, University Medical Center Rotterdam, Wytemaweg 80, Rotterdam 3015 CN, The Netherlands.

Immunology letters
|July 14, 2023
PubMed
概括

T-bet+B细胞可以防止病毒,但也会导致自身免疫性疾病. 遗传因素和爱斯坦-巴尔病毒 (EBV) 影响这些细胞如何促进自身免疫,提供新的治疗点.

关键词:
自身免疫性疾病是一种自身免疫性疾病.B细胞分化的过程爱斯坦·巴尔病毒病毒.遗传易感性 遗传易感性致病性 致病性 致病性T-bet (((+) B细胞中的B细胞.

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