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智能材料的最新进展用于眼部药物输送
Xiaojun Wang1, Fuxiao Luan1, Hua Yue2
1Department of Ophthalmology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, PR China; State Key Laboratory of Biochemical Engineering, Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, PR China.
Advanced drug delivery reviews
|July 14, 2023
概括
智能材料为眼部疾病提供先进的解决方案,改善药物输送,尽管存在限制. 本综述探讨了眼部疾病和未来临床转化智能材料的创新.
科学领域:
- 眼科医生 眼科 眼科
- 生物材料科学 生物材料科学
- 药物运输 药物运输 药物运输
背景情况:
- 眼部药物治疗面临的挑战包括由于疾病的复杂性和自然障碍而导致的目标,透和保留不良.
- 生物医学材料已经发展到一个高度.
- 聪明的聪明的聪明的聪明的聪明
- 这一阶段,为眼部疾病提供了潜在的解决方案.
研究的目的:
- 审查用于治疗常见眼部疾病的智能材料的最新进展.
- 讨论这些智能材料的临床翻译的挑战和未来前景.
主要方法:
- 关于用于治疗眼部疾病的智能材料的综合文献综述.
- 分析各种智能材料类型,包括无机颗粒,聚合物颗粒,基于脂质的颗粒,水凝和设备.
主要成果:
- 智能材料在解决常规眼部药物输送的局限性方面表现有前途.
- 目前正在探索各种智能材料平台,以应对各种眼部疾病.
结论:
- 智能材料代表了治疗眼部疾病的重大发展,尽管仍然存在挑战.
- 为了在眼科中成功的临床翻译智能材料,需要进一步的研究和开发.
相关概念视频
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The selection of a drug's delivery route depends upon its physicochemical properties, including lipid or water solubility and ionization, as well as the therapeutic requirement, such as immediate or sustained effect. These routes can be divided into three primary categories: enteral, parenteral, and topical.
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
Enteral delivery involves administering drugs directly through swallowing, sublingual placement, or buccal application. Orally administered drugs predominantly navigate the...
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Drug Delivery: Miscellaneous Routes
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Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
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