在使用毒品的女性中,艾滋病毒风险感知,暴露前预防 (PrEP) 意识和PrEP启动意图
Caroline K Darlington1, Rachele K Lipsky2, Anne M Teitelman3
1University of Pennsylvania School of Nursing, Philadelphia, PA, USA.
Journal of substance use and addiction treatment
|July 14, 2023
概括
使用药物 (WWUD) 的女性患艾滋病毒的风险较高,但暴露前预防 (PrEP) 摄入量较低. 处方阿片类药物和多种药物的使用与更高的HIV风险感知和PrEP启动意图相关,但意识较低.
科学领域:
- 公共卫生 公共卫生
- 传染病流行病学 传染病流行病学
- 药物使用研究研究 药物使用研究
背景情况:
- 吸毒妇女 (WWUD) 面临着由于生物学,行为和情境因素而导致艾滋病毒感染的风险增加.
- 尽管符合资格,但暴露前预防 (PrEP) 的吸收在WWUD中仍然不够理想.
- 了解药物使用模式和PrEP吸收前体之间的联系对于这个人群至关重要.
研究的目的:
- 描述特定药物使用类型和PREP吸收路线和前体之间的关系.
- 为了确定影响妇女使用药物PrEP吸收的因素.
- 为了在这个人口群体中增加PrEP使用,为目标干预提供信息.
主要方法:
- 一项基于计算机的调查对纽约和费城的233名艾滋病毒阴性, cisgender 妇女进行了调查,她们不是在使用 PrEP,但有资格.
- 收集的数据包括艾滋病毒风险感知,PrEP意识,PrEP启动意图以及使用各种物质 (例如阿片类药物,可卡因,海洛因,甲基胺).
- 分析重点关注与药物使用模式相关的PrEP吸收前体的相关性.
主要成果:
- 在入学三个月内,63.1%的人报告使用毒品,42%的人使用多种药物,19.8%的人注射毒品.
- 使用处方阿片类药物或多种药物的女性认为艾滋病毒风险更高,并打算更频繁地启动PrEP.
- 然而,这些群体和注射毒品的女性显示PrEP意识较低.
结论:
- 调查结果强调,需要针对PrEP和艾滋病毒暴露模式进行量身定制的教育,以提高WWUD的吸收率.
- 干预措施应针对特定子组的PrEP意识较低,包括使用处方阿片类药物,多种药物或注射药物的子组.
- 解决药物使用模式是提高PrEP使用率和降低弱势女性艾滋病毒发病率的关键.
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