迫切需要采用拉流逻辑来供应红细胞以满足患者的需求:一个单一中心研究
Corentin Streel1, Marie Pouplard2, François Laporte3
1Blood Transfusion Service, Cliniques Universitaires Saint-Luc, 1200 Brussels, Belgium; Institute of Experimental and Clinical Research, UCLouvain, 1200 Brussels, Belgium.
概括
患者血液管理 (PBM) 减少了红细胞 (RBC) 输血,但可能导致OD阴性短缺. 优化O-D阴性血液供应需要了解患者的血型需求,并适应捐赠中心的策略.
科学领域:
- 输血医学 输血医学
- 血液银行 血液银行
- 医疗保健管理的管理
背景情况:
- 患者血液管理 (PBM) 计划在比利时减少了红细胞 (RBC) 输血.
- 尽管总体减少了,但OD阴性红细胞的慢性短缺仍然存在.
- 人口结构的变化和种族差异影响了血型需求.
研究的目的:
- 为了分析在学术医院的OD阴性血液使用模式.
- 确定优化O D-负红细胞供应的策略.
- 为了解决患者需求与血液供应之间的差异.
主要方法:
- 在圣卢克大学诊所 (Cliniques universitaires Saint-Luc) (2019-2021) 进行了49823次红细胞输血的回顾性分析.
- 患者血型与供应和输血的红细胞单位的比较.
- 与患者人口统计学相关的输血实践的评估.
主要成果:
- 患者血型分布显示O (47.9%) 和B (10.3%) ABO类型和R0r (8.6%) Rh类型的患病率较高,与高加索标准不同.
- 只有三分之二的可用O D 阴性红细胞被输给了具有相容O rr或R0r血型的患者.
- 观察到患者血型要求与红细胞单元利用之间存在重大不匹配.
结论:
- 在捐赠者/患者群体中,PBM的实施和种族不平衡导致了OD阴性缺乏.
- 准确评估患者血型需求对于资源分配至关重要.
- 献血中心应采用"拉流"供应模式,以满足不断变化的医院需求.
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