菌 (Faecalibacterium):一种具有有前途的人类健康应用的细菌属
Rebeca Martín1, David Rios-Covian1, Eugénie Huillet1
1Paris-Saclay University, INRAE, AgroParisTech, Micalis Institute, 78350, Jouy-en-Josas, France.
FEMS microbiology reviews
|July 14, 2023
概括
肠道细菌Faecalibacterium的低水平与炎症性肠病 (IBD) 和其他疾病有关. 研究支持其作为下一代益生菌 (NGP) 用于肠道健康.
科学领域:
- 微生物学 微生物学
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
背景情况:
- 肠道微生物群组成的变化与各种人类疾病有关.
- 减少Faecalibacterium属的丰富性与炎症状况有关,如炎症性肠病 (IBD),结直肠癌 (CRC),皮肤炎和抑郁症.
- 便细菌水平往往反映了整体肠道健康状况,在患有胃肠道疾病的人群中减少.
结论:
- 流行病学和实验证据支持Faecalibacterium作为下一代益生菌 (NGP) 或活生物治疗产品 (LBP) 的潜力.
- 调节Faecalibacterium水平可能为各种健康状况提供治疗益处.
- 对Faecalibacterium机制的进一步研究可以促进肠道健康干预.
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