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在实验室中通过新型手部卫生设备通过臭氧化水激活SARS-CoV-2
Robert M Lubitz1, Brian R Leon1, K Nicole Bradner2
1School of Medicine, Indiana University, Indianapolis, IN 46256, USA.
Journal of applied microbiology
|July 14, 2023
概括
臭氧化水通过新型喷雾装置应用,有效消毒表面,减少了SARS-CoV-2三角形变体超过99.99%. 这为表面卫生和对抗病毒提供了一个有前途的新方法.
科学领域:
- 微生物学 微生物学
- 传染性疾病 传染性疾病
- 环境科学 环境科学
背景情况:
- 由于COVID-19的流行,需要先进的表面消毒剂和手部卫生方法.
- 臭氧气是一种强效的消毒剂,但其毒性限制了人类直接应用.
- 臭氧化水为消毒提供了更安全的替代方案,特别是用于人类的消毒剂,但其对SARS-CoV-2的有效性仍未得到充分研究.
研究的目的:
- 评估臭氧化水在消除严重急性呼吸系统综合征冠状病毒-2 (SARS-CoV-2) 的有效性.
- 评估一款设计用于输送臭氧化水用于表面消毒的新型手部卫生设备.
主要方法:
- 使用了一种新型的手部卫生装置,产生稳定的臭氧化水 (0.5 +/-0.1 ppm),具有受控的喷雾特性.
- 已知数量的SARS-CoV-2三角形变异被应用于玻璃表面,并用臭氧化水处理七秒钟.
- 病毒生长量化,并使用斯皮尔曼-卡伯方法与未暴露的对照组进行比较.
主要成果:
- 臭氧化水处理导致SARS-CoV-2病毒生长的平均log10减少4.33.
- 与对照组相比,病毒颗粒减少了99.99%以上.
- 这种新型喷雾装置证明了臭氧化水的持续输送.
结论:
- 臭氧化水,当使用专门的喷雾手部卫生装置应用时,在对SARS-CoV-2的表面消毒方面表现出高效.
- 这些发现支持臭氧化水作为控制表面SARS-CoV-2污染的可行工具的潜力.
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