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Updated: Jul 23, 2025

Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes
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Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes

Published on: March 12, 2013

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在左心房肌瘤中,KIF1C和PRKAR1A之间的交叉交叉

Mengchen Zhou1,2,3, Yan Yao4, Xiangyi Wang2

  • 1Department of Cardiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China.

Communications biology
|July 14, 2023
PubMed
概括

心脏肌瘤 (CM) 中罕见的KIF1C基因变异减少其表达,影响PRKAR1A水平并促进瘤生长. 这项研究揭示了一种涉及KIF1C和PRKAR1A在左心房髓瘤 (LAM) 发病过程中的新途径.

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Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
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