怀孕期间高血压疾病与孕产妇和新生儿结局之间的关联:回顾性索赔分析
Samantha G Bromfield1, Qinli Ma1, Andrea DeVries1
1Health Services Research, Elevance Health, Indianapolis, IN, USA.
BMC pregnancy and childbirth
|July 14, 2023
概括
怀孕期间的高血压疾病,尤其是产前,显著增加了母亲和新生儿的风险. 肥胖和先前的妊娠前史预测进展到更严重的高血压状况.
科学领域:
- 产科和妇科 产科和妇科
- 孕产妇和胎儿医学 孕产妇和胎儿医学
- 公共卫生 公共卫生
背景情况:
- 妊娠高血压疾病的患病率正在增加.
- 这些情况与母亲和新生儿的不良结果以及母亲未来的心血管风险有关.
研究的目的:
- 评估怀孕期间高血压疾病与母亲/新生儿结局之间的关联.
- 为了确定妊娠期间高血压疾病进展的危险因素.
主要方法:
- 一个倾向匹配的回顾性队列研究,使用国家医疗补助申请数据.
- 包括有或没有高血压疾病的母亲 (孕期高血压,慢性高血压,孕前,叠加孕前) 和他们的婴儿.
- 使用回归模型来比较结果和逐步后勤回归来确定进展风险因素.
主要成果:
- 孕前和叠加孕前与剖腹产,早产,呼吸困扰综合征和低出生体重的风险显著增加有关.
- 孕期高血压的结果与没有高血压的结果相似,而慢性高血压则处于两者之间.
- 肥胖/超重以及先前的妊娠前史是进展到更严重的高血压疾病的强有力的预测因素.
结论:
- 孕前或叠加孕前的母亲和新生儿面临的不良结果大幅增加.
- 孕期高血压带来最小的风险,而慢性高血压带来中间风险.
- 肥胖和先前的妊娠前史是妊娠期间高血压进展的关键风险因素.
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