诊断为COVID-19-A队列研究的患者和没有患者的住院结果
Claire Ufongene1, Grace Van Hyfte2, Parul Agarwal2,3
1Icahn School of Medicine at Mount Sinai (ISMMS), New York, New York, USA.
Epilepsia
|July 15, 2023
概括
患有2019年冠状病毒病 (COVID-19) 和的患者经历了更长的住院时间和更多的非例行出院. 在这个群体中,年龄较大,使用呼吸机和并发症增加了死亡风险.
科学领域:
- 神经学 神经学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 冠状病毒疾病2019 (COVID-19) 与死亡率的增加有关,特别是在具有先前疾病的个体中.
- 是一种常见的并发症,可能会影响COVID-19的结果.
研究的目的:
- 为了调查被诊断为COVID-19的患者的住院结果,比较患有和没有的人.
- 在COVID-19患者中确定与死亡率和非例行出院相关的因素.
主要方法:
- 一项回顾性研究分析了2020年3月至2021年5月期间入院的9833名COVID-19患者的数据.
- 使用经过验证的ICD-9-CM/ICD-10-CM病例定义确定了.
- 后勤回归和卡普兰-梅尔分析评估了死亡率和出院状态;普通最小平方回归评估了逗留时间.
主要成果:
- 与没有的患者相比,患者 (n=334) 在单变量分析中显示出更高的呼吸机使用率,ICU入院率,死亡率和更长的入院时间 (LOS).
- 多变量分析显示,在患者中,非例行性放出 (aOR 2.70) 和较长的LOS (32.50%) 的几率显著更高.
- 与患者死亡率增加相关的因素包括年龄较大 (≥65岁),呼吸机支持和较高的查尔森并发症指数 (CCI).
结论:
- 患有COVID-19和的个体有非例行出院的几率增加和更长的LOS,但死亡率没有显著上升.
- 患有和多种并发症的老年人代表了一个脆弱的人群,在COVID-19爆发期间需要密切监测.
- 这些发现凸显了针对COVID-19患者的量身定制护理策略的需要,特别是那些年龄较大且有重大并发症的患者.
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