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Updated: Jul 23, 2025

Mass Spectrometry and Luminogenic-based Approaches to Characterize Phase I Metabolic Competency of In Vitro Cell Cultures
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卡西位异构体的体外代谢:性别是否重要?

Peng Che1,2, J Tyler Davidson3, Kristina Still1,2

  • 1Division of Bioanalytical Chemistry, Department of Chemistry and Pharmaceutical Sciences, Amsterdam Institute of Molecular and Life Sciences (AIMMS), Vrije Universiteit Amsterdam, De Boelelaan 1085, 1081 HV, Amsterdam, The Netherlands.

Analytical and bioanalytical chemistry
|July 15, 2023
PubMed
概括

这项研究探讨了使用男性和女性肝脏显微体的甲基甲基 (MMC) 代谢. 在雄性大鼠中发现了七种性别特异性代谢物,突出显示了药物处理中的潜在差异.

关键词:
在体外代谢的代谢.甲基甲基甲氨基.位置性异构体的位置性异构体.性别特定的差异.合成的卡西诺.

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