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良性质瘤是一种良性质瘤.

Peter B Wu1, Anna C Filley2, Michael L Miller3

  • 1Department of Neurosurgery, David Geffen School of Medicine at UCLA, UCLA, Los Angeles, USA.

Advances in experimental medicine and biology
|July 15, 2023
PubMed
概括
此摘要是机器生成的。

低级质瘤 (LGG) 是缓慢生长的大脑瘤,被世界卫生组织分类为I级或II级. 虽然有些人可以通过手术治愈,但有些人会转变为恶性瘤,需要根据分子特征量身定制的治疗策略.

关键词:
血管中心性质瘤冠状腺质瘤 冠状腺质瘤扩散性星球细胞瘤是什么扩散性小腺瘤 (Oligodendroglioma) 是一种低度结质瘤是低度的结质瘤.皮洛细胞性星系细胞瘤皮洛米克索类天体细胞瘤形的桑托阿斯特罗细胞瘤.亚独立的巨细胞星瘤.作为一个独立的群体,它是次要的.

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科学领域:

  • 神经瘤学神经瘤学
  • 分子遗传学 分子遗传学
  • 瘤的分类 瘤的分类

背景情况:

  • 良性质瘤,也称为低级质瘤 (LGG),是异质的,生长缓慢的瘤,被世界卫生组织分类为I级或II级.
  • 分子遗传学的进步显著改善了对质瘤瘤发生和分类的理解.
  • 世卫组织2016年分类强调分子特征,以准确诊断质瘤.

研究的目的:

  • 审查各种良性质瘤亚型的共同和独特特征.
  • 讨论LGG的诊断标准,治疗策略和预后影响.
  • 为了突出 Glioma 分类和管理的不断变化的理解.

主要方法:

  • 关于良性质瘤和低度质瘤 (LGG) 的当前文献的综述.
  • 基于世卫组织中央神经系统瘤分类的诊断标准的讨论.
  • 分析分子遗传学,治疗选择 (手术,化疗,放射治疗) 和预后因素.

主要成果:

  • 良性结质瘤被广泛分为焦点,周围的病变 (世卫组织I级) 和扩散性结质瘤 (世卫组织II级).
  • 儿科患者的世卫组织I级瘤通常仅通过手术切除就有很好的预后.
  • 扩散性结质瘤具有透性生长模式,倾向于复发,并且可以经历恶性转变,需要综合管理.

结论:

  • 良性质瘤的预后有很大差异,非透性类型通常具有很好的前景.
  • 最大安全的手术切除是初级和复发性LGG的主要治疗方法.
  • 分子特征对于准确诊断,治疗计划和预测低度质瘤的预后至关重要.