良性脑和脊髓瘤起源于骨或软骨
Abhishek Gami1, Andrew Schilling1, Jeff Ehresman1
1Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Advances in experimental medicine and biology
|July 15, 2023
概括
良性脊柱瘤是罕见的,但多样化,包括骨质细胞和软骨形成的病变. 治疗方法各不相同,往往需要多学科的方法和手术切除,以防止复发.
科学领域:
- 整形瘤学 整形瘤学
- 脊柱外科手术 脊柱外科手术
- 在瘤学瘤学.
背景情况:
- 良性骨骨性脊柱瘤并不常见,占主要骨瘤的1-13%.
- 这些包括骨质细胞 (骨质骨质瘤,骨质母细胞瘤) 和形成软骨的 (骨质母细胞瘤,骨质母细胞瘤,骨质母细胞瘤) 病变.
- 其他良性脊髓瘤包括动脉瘤骨囊,巨细胞瘤和eosinophilic颗粒瘤.
研究的目的:
- 审查流行病学,分子生物学,成像学和良性脊髓瘤治疗方面的异质性.
- 突出基于瘤类型和呈现的各种治疗策略.
- 强调在管理这些病变时采用多学科方法的重要性.
主要方法:
- 文献综述和关于良性脊髓瘤的当前知识的综合.
- 讨论手术规划的分类系统 (恩尼金,韦恩斯坦-博里亚尼-比亚吉尼).
- 传统和新型治疗方法的概述,包括手术,射频切除和化疗.
主要成果:
- 在良性脊髓瘤的特征和管理方面存在显著的异质性.
- 骨质骨质瘤对抗炎药物有反应,而其他骨质母细胞瘤可能需要手术干预.
- 整体切除通常是首选的,以尽量减少复发风险.
结论:
- 良性脊柱瘤由于其多样性而需要量身定制的管理策略.
- 多学科的团队方法对于最佳的患者结果至关重要.
- 手术和化疗选择,以及新技术,是治疗的组成部分.
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