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接受肥胖治疗的儿童和青少年的身高和生长速度:一项前性队列研究
Resthie R Putri1, Pernilla Danielsson1, Claude Marcus1
1Division of Pediatrics, Department of Clinical Science, Intervention, and Technology, Karolinska Institutet, Stockholm 141 57, Sweden.
The Journal of clinical endocrinology and metabolism
|July 15, 2023
概括
儿童肥胖症的严重程度会影响儿童的身高和生长速度. 虽然严重的肥胖可能会阻碍青春期的生长冲刺,但成功的治疗可以使生长模式正常化,而不会造成长期伤害.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 增长和发展 增长和发展
- 肥胖问题研究研究
背景情况:
- 儿童肥胖与内分泌条件有关,这些条件可能会影响生长.
- 了解肥胖严重程度和治疗对儿童生长的影响至关重要.
研究的目的:
- 研究肥胖严重程度 (I级与II级) 如何影响儿童的成长.
- 评估肥胖治疗结果对随着时间的推移增长速度的影响.
主要方法:
- 在瑞典儿童肥胖治疗登记册 (BORIS) (1998-2020) 中对27,997名儿童 (3-18岁) 进行前性队列研究.
- 按I和II类分类的肥胖症;按BMIz-score变化 (好,中等,差) 计算治疗结果.
- 比较身高与年龄的z-score,最终身高和生长速度;分析了2年随访期间的生长速度.
主要成果:
- 在男性和女性中,II类肥胖与更高的童年身高和减少/不存在的青春期生长冲击有关.
- 良好的肥胖治疗结果显示较低的增长速度 (3-9岁),但较高的增长速度 (10-13岁) 与糟糕的结果相比.
- 肥胖的严重程度与儿童时期的身高和生长速度正相关.
结论:
- 肥胖的严重程度与儿童时期的身高和生长速度有关.
- 预计在青春期,特别是严重肥胖时,会出现阻碍成长的冲刺;最终的身高预计在所有肥胖类别中都是相似的.
- 成功的肥胖治疗使生长速度模式正常化,这表明它不是有害的.
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