肺下左心室大小和功能在患有全身右心室患者的预后意义
Elena Surkova1,2,3, Andrew Constantine1,2, Zhuoyuan Xu1
1Adult Congenital Heart Centre and Centre for Pulmonary Hypertension, Royal Brompton Hospital, Royal Brompton and Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, Sydney St, London SW3 6NP, UK.
European heart journal. Cardiovascular Imaging
|July 15, 2023
概括
系统右心室 (SRV) 和肺下左心室 (LV) 的心声扫描对于预测SRV成人的死亡率和移植风险至关重要. LV的大小和功能是风险分层的关键指标.
科学领域:
- 心脏病学 心脏病学
- 儿童心脏病学 儿童心脏病学
- 心脏成像 - - 心脏成像
背景情况:
- 系统右心室 (SRV) 生理学在成人先天性心脏病中提出了独特的挑战.
- 准确的风险分层对于管理SRV患者至关重要,通常涉及复杂的外科病史.
研究的目的:
- 评估SRV患者肺下左心室 (LV) 大小和功能的心声测量结果的预后价值.
- 为了确定LV参数是否提供了SRV评估之外的额外预测信息.
主要方法:
- 在2010年至2018年期间,对180名SRV成人患者进行了回声心脏成像的回顾性分析.
- 评估双心室大小和功能,重点关注SRV和肺下LV参数.
- 考克斯多变量分析和接收器操作特征 (ROC) 分析,以确定死亡率或移植的预测因素.
主要成果:
- 索引LV末缩直径 (ESDi) 和SRV基底直径与风险增加有关.
- LV 分数面积变化 (FAC) 和 SRV FAC 与风险降低有关.
- 在ROC分析中,肺下LV参数与SRV标志物相比显示出更好的预测性能.
结论:
- 对SRV基底直径,SRV FAC,LV ESDi和LV FAC的心声学评估是不良结果的独立预测指标.
- 对于SRV患者的风险分层和临床管理,对两个心室进行全面的心声学评估至关重要.
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