儿科大脑侧静脉血栓和的风险
Alexis R Karlin1, Nankee K Kumar2, Arastoo Vossough3
1Division of Child Neurology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Pediatric neurology
|July 15, 2023
概括
儿科大脑内血栓 (CSVT) 中的急性预测了儿童的. 新生儿和患有的儿童在CSVT后都经历了更糟糕的结果.
科学领域:
- 神经学 神经学
- 儿科中风 儿童中风
- 发病学 (Epileptology) 是一个专业的学科.
背景情况:
- 大脑内血栓 (CSVT) 是儿童罕见但严重的疾病,往往导致严重的长期健康问题.
- 了解发作和随后的发生和预测因素对于管理儿科CSVT至关重要.
研究的目的:
- 确定儿科CSVT后的急性发作,远程发作和的累积发病率.
- 确定这些发作结果的预测因素,并评估它们对长期神经功能的影响.
主要方法:
- 对131名神经成像证实CSVT的新生儿和儿童进行了回顾性分析.
- 发作类型被分为急性 (在7天内) 或远程 (>7天内) 类型,是由反复的远程发作定义的.
- 使用生存分析方法来确定发病率和风险因素.
主要成果:
- 急性发作发生在42%的新生儿和19%的儿童中. 出血是儿童急性发作的一个预测因素.
- 发作发生在5/6个新生儿和10/14个经历远程发作的儿童中.
- 计算了1年和3年的无生存率,在患有的患者中观察到更差的儿科中风结局测量得分.
结论:
- 急性发作是患有CSVT的儿童的重要危险因素.
- 在CSVT后的新生儿和儿童中的存在与整体结果较差有关.
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