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Updated: Jul 23, 2025

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair
08:15

gDNA Enrichment by a Transposase-based Technology for NGS Analysis of the Whole Sequence of BRCA1, BRCA2, and 9 Genes Involved in DNA Damage Repair

Published on: October 6, 2014

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通过遗传性癌症小组检测到的不常见变体以及对遗传咨询的建议

Zeynep Özdemir1, Ezgi Çevik1, Ömür Berna Çakmak Öksüzoğlu2

  • 1Ankara Etlik City Hospital, Department of Medical Genetics, Ankara, Turkiye.

Mutation research
|July 15, 2023
PubMed
概括

下一代测序在13.7%具有遗传性癌症倾向的个体中发现了致病变体. 这项研究强调了土耳其人口中罕见基因突变的流行,有助于个性化遗传咨询.

关键词:
遗传性癌症综合征 遗传性癌症综合征多基因面板测试测试多基因面板测试下一代测序测序是什么

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Targeted Next-generation Sequencing and Bioinformatics Pipeline to Evaluate Genetic Determinants of Constitutional Disease09:34

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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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