相关实验视频

Updated: Jul 23, 2025

In Ovo Intravascular Injection in Chicken Embryos
07:00

In Ovo Intravascular Injection in Chicken Embryos

Published on: June 3, 2022

6.1K

LIN28对于维持的原始生殖细胞至关重要

Katsuya Suzuki1, Seung June Kwon1, Daisuke Saito1

  • 1Department of Biology, Faculty of Science, Kyushu University, Fukuoka 819-0395, Japan.

Cells & development
|July 15, 2023
PubMed
概括

LIN28A和LIN28B对于维持原始生殖细胞 (PGC) 的自我更新和殖民至关重要. 通过抑制EGR1,LIN28等分化基因,可以确保PGC的扩散和成功的性腺殖民.

关键词:
肉 肉 肉 肉基因编辑 基因编辑在LIN2828上,我们可以看到.一个原始的生殖细胞.自我更新是一种自我更新.

更多相关视频

Separation of Avian Preovulatory Follicle Granulosa and Theca Cell Layers for Downstream Applications05:04

Separation of Avian Preovulatory Follicle Granulosa and Theca Cell Layers for Downstream Applications

Published on: October 25, 2024

638
Grafting of Beads into Developing Chicken Embryo Limbs to Identify Signal Transduction Pathways Affecting Gene Expression11:48

Grafting of Beads into Developing Chicken Embryo Limbs to Identify Signal Transduction Pathways Affecting Gene Expression

Published on: January 17, 2016

8.9K

相关概念视频

Maintenance of the ES Cell State01:14

Maintenance of the ES Cell State

The cells of the blastocyst inner cell mass only remain pluripotent for a short time. This state of pluripotency and self-renewal can be maintained in embryonic stem (ES) cell culture by adding specific chemicals or growth factors to ensure the cells can continue dividing and later differentiate into different cell types. In some cases, the cells are grown on a feeder layer of differentiated cells, which provides the growth factors and extracellular matrix components necessary for stem cell...
2.2K
Role Of Notch Signalling In Intestinal Stem Cell Renewal01:12

Role Of Notch Signalling In Intestinal Stem Cell Renewal

Notch signaling was first discovered in Drosophila melanogaster, where it is involved in cell lineage differentiation. Notch signaling regulates the maintenance and differentiation of intestinal stem cells or ISCs by controlling the expression of atonal homolog 1 or Atoh1. Atoh1 directs cells to differentiate into secretory cells.
Direct cell-to-cell contact is needed for the activation of Notch signaling. The signal is initiated when a notch ligand binds to a receptor on an adjacent cell, also...
2.1K
Gastrulation01:56

Gastrulation

Gastrulation establishes the three primary tissues of an embryo: the ectoderm, mesoderm, and endoderm. This developmental process relies on a series of intricate cellular movements, which in humans transforms a flat, “bilaminar disc” composed of two cell sheets into a three-tiered structure. In the resulting embryo, the endoderm serves as the bottom layer, and stacked directly above it is the intermediate mesoderm, and then the uppermost ectoderm. Respectively, these tissue strata...
57.6K
Renewal of Intestinal Stem Cells01:23

Renewal of Intestinal Stem Cells

The intestinal epithelial lining rapidly renews every 4 to 5 days. The renewal is facilitated by intestinal stem cells (ISCs) located at the base of the crypt– a gland located at the bottom of each villus. ISCs divide asymmetrically to form new stem cells and progenitor daughter cells. The daughter cells are called transit-amplifying (TA) cells which move upwards along the crypt and either differentiate into absorptive cells– the enterocytes or secretory cells– including the...
2.6K
Lineage Commitment01:21

Lineage Commitment

Commitment is the  process whereby stem cells:
3.0K
Zygotic Development And Stem Cell Formation01:10

Zygotic Development And Stem Cell Formation

The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a totipotent cell that can develop into a complete organism. The zygote undergoes cell division or cleavage to form an 8-cell mass. Until this stage, the cells are spherical, loosely attached, and remain totipotent. Totipotent cells are capable of developing both the embryonic and the extraembryonic tissues. However, as they continue to divide, they...
5.3K